A Missing Link in Genotype-Directed Cancer Therapy
نویسنده
چکیده
Genotype-directed therapy holds great promise for the treatment of cancer, but crosstalk between signaling pathways often confounds simple genotype-drug response relationships. To deliver on the promise of precision medicine, a coordinated effort is needed to make a comprehensive inventory of the many signaling feedback circuits that exist in cancer cells.
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عنوان ژورنال:
- Cell
دوره 151 شماره
صفحات -
تاریخ انتشار 2012